The Sleep Resource Core (SRC) will be integrated into this SCORE by providing equipment, analysis, sleep- related expertise, and sleep data to the two human, one animal, and relevant Career Enhancement Core projects. The scientific leadership and technical support to facilitate and integrate rigorous collection, processing, analysis, and interpretation of sleep measures, will enable the SRC to promote interdisciplinary, collaborative, synergistic, and translational work and support the scientific and career enhancement goals of this SCORE. This work will expand the scientific impact of the SCORE by including sleep as a key health measure in human and animal models of women’s health and aging, including impacts on response to stress; body composition; neurological, cardiovascular, reproductive, and metabolic function; cognition; and mental health.
*ROSA Affiliated Authors shown in bold
“Keeping an eye on circadian time in clinical research” Clinical and Translational Medicine. Klerman EB, Brager A, Carskadon MA, Depner CM, Foster R, Goel N, Harrington M, Holloway PM, Knauert MP, LeBourgeois MK, Lipton J, Merrow M, Montagnese S, Ning M, Ray D, Scheer FAJL, Shea SA, Skene DJ, Spies C, Staels B, St-Onge MP, Tiedt S, Zee PC, Burgess HJ.
“From Bench to Bedside and Back Again: translating circadian science to medicine” Journal of Biological Rhythms. Klerman EB, Kramer A, Zee PC.
“Beyond the symptom: the biology of fatigue” SLEEP. Raizen DM, Mullington J, Anaclet C, Clarke G, Critchley H, Dantzer R, Davis R, Drew KL, Fessel J, Fuller PM, Gibson EM, Harrington M, Lipkin WI, Klerman EB, Klimas N, Komaroff AL, Koroshetz W, Krupp L, Kuppuswamy A, Lasselin J, Lewis LD, Magistretti PJ, Matos HY, Miaskowski C, Miller AH, Nath A, Nedergaard M, Opp MR, Ritchie MD, Rogulja D, Rolls A, Salamone JD, Saper C, Whittemore V, Wylie G, Younger J, Zee PC, Heller HC.
“Consensus Recommendations for Standardized Data Elements, Scales, and Time Segmentations in Studies of Human Circadian/Diurnal Biology and Stroke” Stroke. Saver JL, Klerman EB, Buchan AM, Calleja P, Lizasoain I, Bahr-Hosseini M, Lee S, Liebeskind DS, Mergenthaler P, Mun KT, Ning M, Pelz D, Ray D, Rothwell PM, Seners P, Sreekrishnan A, Sung EM, Tiedt S, Webb AJS, Wölfer TA, Albers GW; CIRCA.
“The organization of sleep-wake patterns around daily schedules in college students” SLEEP. Lu S, Stone JE, Klerman EB, McHill AW, Barger LK, Robbins R, Fischer D, Sano A, Czeisler CA, Rajaratnam SMW, Phillips AJK.
The Career Enhancement Core (CEC) will train the next generation of investigators in women’s health and sex-differences research through cutting-edge SCORE Scholars and Pilot Project Awards, Travel Exchange Fellowships, multidisciplinary career development, and innovative educational programs.
The role of the Leadership Administrative Core (LAC) is to integrate and unify the multiple, interdisciplinary components of the Brigham/Harvard Center. The LAC will provide scientific, administrative, and fiscal oversight of our SCORE Projects, Career Enhancement Core, and Sleep Resource Core, and will catalyze progress and innovation in women’s health and sex- differences research across the Brigham/Harvard SCORE environment. The LAC also will lead collaborations between the Brigham/Harvard SCORE and the nationwide SCORE network.
